U.S. Bio-Chem Medical Services

Hepatitis B core Ab Test
Fasting Required: No Specimen: Blood Results: 5-7 Business Days Description: Can be used to help detect acute and chronic HBV infections; the IgM antibody is the first antibody produced after infection with HBV; IgG antibody is produced in response to the core antigen later in the course of the infection and usually persists for life. Methodology Immunoassay (IA) Limitations Results obtained from immunosuppressed patients should be interpreted with caution. Patients receiving mouse antibody therapy may produce false-negative results. False-positives may be detected shortly after immunication to influenza and with patients with hypergammalobulinemia, positive rheumatoid factor, and connective tissue disorders. Clinical Significance This assay does not distinguish between Total B core antibody IgG and IgM detected before or at the onset of symptoms; however, such reactivity can persist for years after illness, and may even outlast anti-HBs. Occasionally Hepatitis B core antibody may be the only marker of either current or past Hepatitis B infection.