U.S. Bio-Chem Medical Services

SINCE 1961

Herpes S Virus Test, I/II specific
Fasting Required: No Specimen: Blood Results: 5-7 Business Days Description: IgG antibodies indicate a previous infection. Herpes simplex virus 1 (HSV-1) typically causes oral herpes, an infection of the lips and mouth, that is commonly known as cold sores or fever blisters. Genital herpes is generally caused by herpes simplex virus 2 (HSV-2). The herpes simplex virus is transmitted by direct contact with a sore or the body fluid of an infected individual. Methodology Immunoassay (IA) Limitations Individuals infected with HSV may not exhibit detectable IgG antibody in the early stages of infection. Clinical Significance Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients.