U.S. Bio-Chem Medical Services

Varicella Zoster IgG
Fasting Required: No Specimen: Blood Results: 3-5 Business Days Description: Varicella zoster virus (VZV) causes the illness known as chicken pox. Although most (85-90%) pregnant women have already been exposed to the virus and therefore are immune, some may not have previously had the infection. Since the virus can cause birth defects or illness in the baby (depending on when during the pregnancy an infection occurs), testing is available pre-conception or in early pregnancy to determine if the woman has antibodies to VZV. If she doesn’t and is therefore not immune, a vaccine can be given before the woman gets pregnant; if she is already pregnant and may have been exposed to the virus, treatment is available that can prevent or weaken the severity of the illness. Methodology: Immunoassay (IA) Limitations: Other herpes viruses may cross react and produce high titers. Protection may be limited at low positive titers. Antibodies persist after infection has been treated or becomes dormant. Clinical Significance: Varicella-Zoster Virus (VZV) causes chicken pox and when reactivated, potentially decades later, causes shingles. Twenty percent of adults will develop shingles, a rash or blister of the skin that may cause severe pain. Varicella-Zoster IgG, EIA reliably measures immunity due to previous infection, but is unsuitable for detection of post-vaccination immune status. Alternative Name(s): Herpes Zoster,Shingles,Chicken Pox